This science fair project aims to validate the effectiveness of acne medications in preventing the growth of bacteria. This experiment will be carried out using 3 types of acne medication – Tetracycline, Clindamycin and Benzoyl peroxide.
Acne medications effectively inhibit the growth of bacteria that causes acne.
Acne, pilosebaceous unit, sebaceous gland, sebum, Propionibacterium acne (P acne), follicles, enzyme, fatty acids, Tetracycline, Clindamycin and Benzoyl peroxide
Acne occurs in the pilosebaceous unit that consists of a hair shaft, a sebaceous gland and a hair follicle. These units are present in higher numbers on our face, neck and chest areas. These sebaceous glands help keep our hair and skin moisturized by producing a substance called sebum.
Propionibacterium acne (P. acne) bacteria are normally found living on the surface of our skin. It uses the sebum produced by the sebaceous gland as a nutrient for its survival . People with acne problems have greater amounts of P. acne in their follicles. White blood cells are attracted to the presence of P. acne and they release an enzyme that damage the follicle walls. This process causes inflammation which is aggravated by the presence of fatty acids produced by P. acne.
Among the common acne medications are Tetracycline which helps in reducing the inflammatory lesions. Clindamycin is an antibiotic that helps to destroy P. acne and alleviate inflammations. Benzoyl peroxide helps destroy P. acne but does not have anti-inflammatory properties.