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Project title Examine the interactions of class A and C ß-lactamases as they interact with ß-lactam antibiotics.
Difficulty Level High school
Main link Click here to view all details of this science project (Cached)

Description
ß-lactamases are the principal agents of bacterial resistance to many penicillins, cephalosporins, and other ß-lactam antibiotics. The main objective is to understand the interactions of class A and C ß-lactamases as they interact with ß-lactam antibiotics in order to model a non-ß-lactam inhibitor into the active site. This would stop the hydrolytic power of ß-lactamases and rejuvenate ß-lactam antibiotics. 

Materials
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Brief Instructions
[Please see third-party website for instructions]
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