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Topics > Microbiology > Virology

	Project title	What is the effect of the Influenza A Virus Infection on Nasopharyngeal Colonization?
	Difficulty Level	High school
	Main link	Click here to view this science project
Description
Phase variation in the colonial opacity of Streptococcus pneumoniae has been implicated as a factor in bacterial adherence, colonization, and invasion in the pathogenesis of pneumococcal disease. Additionally, the synergistic effects of influenza A virus and S. pneumoniae in the development of otitis media (OM) have been reported. This study examined the ability of opaque or transparent S. pneumoniae from the same strain in combination with an antecedent influenza A virus infection to colonize the nasopharynx and invade the middle ear in the chinchilla model.
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Brief Instructions
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