Science Fair Project Encyclopedia
APV blocks the cellular analog of classical conditioning in the sea slug Aplysia californica, and has similar effects on Aplysia long-term potentiation, since NMDA receptors are required for both. It is sometimes used in conjunction with the calcium chelator BAPTA to determine whether NMDARs are required for a particular cellular process.
APV can block the conversion of a silent synapse to an active one, since this conversion is NMDA receptor-dependent.
APV was developed by Jeff Watkins .
- Cellular Analog of Differential Classical Conditioning in Aplysia: Disruption by the NMDA Receptor Antagonist DL-2-Amino-5-Phosphonovalerate
APV is also a common abbreviation for avian pneumovirus .
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