Science Fair Project Encyclopedia
Activin
Activin is a peptide that enhances FSH synthesis and secretion and participates in the regulation of the menstrual cycle. It does the opposite as inhibin.
Structure
Activin contains two beta subunit that are identical to the two beta subunits (A or B) of inhibin, allowing for the formation of three forms of activin: A, AB, and B. Like inhibin (and AMH) activin belongs to the transforming growth factor-β (TGF-β) family.
Action
In the ovarian follicle, activin increases FSH binding and FSH induced aromatization. It participates in androgen synthesis enhancing LH action in the ovary and testis. In the male , activin enhances spermatogenesis. Activin is produced in the gonads, pituitary gland, placenta and other organs.
10-26-2009 08:16:03
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The contents of this article is licensed from www.wikipedia.org under the GNU Free Documentation License. Click here to see the transparent copy and copyright details