Science Fair Project Encyclopedia
Adeno-associated virus
Adeno associated virus is a helper virus , associated with Adenovirus. It is commonly called AAV. It cannot replicate on its own, it requires a cell to be co-infected with Adenovirus in order to replicate. In the absence of co-infection with Adenovirus, the AAV goes into a latent phase . This latent phase makes AAV attractive for gene therapy applications as a gene of interest in AAV can persist in the host cell genome for a long period. AAV is a small parvovirus, its wildtype genome is 4.7kb. This is the upper limit for its use in gene therapy applications as well.
10-26-2009 08:16:03
The contents of this article is licensed from www.wikipedia.org under the GNU Free Documentation License. Click here to see the transparent copy and copyright details
The contents of this article is licensed from www.wikipedia.org under the GNU Free Documentation License. Click here to see the transparent copy and copyright details