Antoine Barthelemy Clot (7 November 1793 - 28 August 1868) was a French physician known as Clot Bey while practicing in Egypt.

He was born at Grenoble, and graduated in medicine and surgery at Montpellier. After practising for a time at Marseilles he was made chief surgeon to Mehemet Ali, viceroy of Egypt. At Abuzabel , near Cairo, he founded a hospital and schools for all branches of medical instruction, as well as for the study of the French language; and, notwithstanding the most serious religious difficulties, instituted the study of anatomy by means of dissection. In 1832 Mehemet Ali gave him the dignity of bey without requiring him to abjure his religion; and in 1836 he received the rank of general, and was appointed head of the medical administration of the country. In 1849 he returned to Marseilles, though he revisited Egypt in 1856. He died at Marseilles in 1868.

His publications included:

• Relation des j~idmies de cholera qui ont ren d lHeesiaz. a Suez, et en Egypte (1832)
• De La Peste observe en Egypte (1840)
• Aperu gnral sur l'Egypte (1840)
• Coup dciil sur la peste et les quarantaines (1851)
• Dc lophthalmie (1864)