Science Fair Project Encyclopedia
Bile acid sequestrant
In pharmacology, bile acid sequestrants a group of medication used for binding bile in the gastrointestinal tract. Its uses are the treatment of hypercholesterolemia and prevention of pruritus (itch) in patients with chronic liver disease or diarrhea.
Two drugs are members of this class; both are synthetic resins:
- Cholestyramine (Questran®)
- Colestipol (Colestid®)
Use of these agents has decreased markedly since the introduction of statins. They are occasionally used as an adjunctive to statins, as the combination of statins and fibrates is thought to increase the likelihood of developing rhabdomyolysis.
10-26-2009 08:16:03
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The contents of this article is licensed from www.wikipedia.org under the GNU Free Documentation License. Click here to see the transparent copy and copyright details