Cackletta is the main villain of Mario & Luigi: Superstar Saga, for the Game Boy Advance.

Aided by Fawful, she wanted to obtain the Beanstar (a mystical object of the Beanbean Kingdom) and steal Princess Peach's voice. It is said that one with a beautiful voice can activate the Beanstar's mysterious powers to grant any wish (and this is what Cackletta was aiming for. She wishes to rule the Beanbean Kingdom and soon after, the Mushroom Kingdom.)

Cackletta was beaten by Mario and Luigi at Woohoo Hooniversity. Her body was battered up so badly, she could no longer move around on her own. Fawful absorbed the remains of Cackletta (into an energy-like form) and made a hasty retreat. Bowser was suffering from amnesia for some time, and just when he remembered who he was, he was possesed by Cackletta!

Now with the new alias, Bowletta, she continues her plan to obtain the Beanstar and Peach's voice. The Mario Bros. eventually caught up with Bowletta and defeated her yet again. And this time, it was for good. Her spirit left Bowser's body and disappeared forever.