Castiglione is the name of several Italian towns:

• Castiglion Fibocchi , in the province of Arezzo
• Castiglion Fiorentino , in the province of Arezzo
• Castiglione a Casauria , in the province of Pescara
• Castiglione Chiavarese , in the province of Genova
• Castiglione Cosentino , in the province of Cosenza
• Castiglione d'Adda, in the province of Lodi
• Castiglione dei Genovesi , in the province of Salerno
• Castiglione dei Pepoli , in the province of Bologna
• Castiglione del Lago , in the province of Perugia
• Castiglione della Pescaia, in the province of Grosseto
• Castiglione delle Stiviere, in the province of Mantova
• Castiglione di Garfagnana , in the province of Lucca
• Castiglione di Sicilia , in the province of Catania
• Castiglione d'Intelvi , in the province of Como
• Castiglione d'Orcia , in the province of Siena
• Castiglione Falletto , in the province of Cuneo
• Castiglione in Teverina , in the province of Viterbo
• Castiglione Messer Marino , in the province of Chieti
• Castiglione Messer Raimondo , in the province of Teramo
• Castiglione Marittimo , in the province of Catanzaro
• Castiglione Olona, in the province of Varese
• Castiglione Tinella , in the province of Cuneo
• Castiglione Torinese , in the province of Torino

Castiglione, Haute-Corse is a commune of the Haute-Corse département in France, on the island of Corsica

Castiglione is also the surname of the famous writer and diplomat Baldassare Castiglione