The most notable woman named Cecily Neville was the mother of Edward IV of England and Richard III of England (see below), but she was not the only one to bear that name.

Richard Neville, Earl of Warwick (known as "the Kingmaker") had a sister named Cecily Neville whose first husband Henry Beauchamp became 1st Duke of Warwick in 1445 and the only King of the Isle of Wight (as well as of Jersey and Guernsey). Her second husband John Tiptoft became 1st Earl of Worcester (in 1449), but little more is known of her.

Cecily Neville (3 May, 1415 - 31 May, 1495), Duchess of York, was called "the Rose of Raby" (because she was born at Raby Castle in Durham, England) and "Proud Cis" (because of her pride and a temper that went with it). She was daughter to Ralph Neville, 1st Earl of Westmorland and Joan Beaufort. Her mother was a grand-daughter of Edward III of England. In 1437, Cecily married Richard, Duke of York, the leader of the House of York in the Wars of the Roses, and two of their sons became kings: Edward IV of England and Richard III of England. She was known for her piety as well as her pride.

Recently, it has been said that her son Edward was really illegitimate and his father was most likely an archer by the name of Blaybourne.