For information on the Duke of Mayenne, see Charles of Lorraine, Duke of Mayenne.

Prince Charles Alexander of Lorraine (December 12, 1712 - July 4, 1780) was the younger brother of Francis Stephen, the last Duke of Lorraine. When Lorraine was given up by his brother in 1737 to allow Francis to marry the Archduchess Maria Theresa, heiress of Emperor Charles VI, he entered the Imperial service. During the War of the Austrian Succession, he was one of the principal Austrian military commanders, and was most notable for his defeat by Frederick the Great at the Battle of Hohenfriedberg in 1745. On January 7, 1744, He married Maria Theresa's sister, Archduchess Maria Anna , thus making him doubly Maria Theresa's brother-in-law, and the pair were jointly made Governors of the Austrian Netherlands. Although Maria Anna died later that year, Charles himself continued as governor until his own death in 1780. He also became Grand Master of the Teutonic Order in 1761.