Science Fair Project Encyclopedia
Chloroquine
Anti-malaria medicine.
Inside the red blood cells, the parasite must degrade the hemoglobine for the acquisition of all the nutrients the parasite needs to survive and multiplicate inside the cell. During this process, the parasite produces the toxic and soluble molecule heme. To avoid destruction by this molecule, the parasite aggregates heme to form hemozoin, an insoble and non-toxic molecule. Chloroquine interferes with this process and prevents the formation of hemazoine. This allows the toxic effect of heme on the parasite, which is killed by this molecule.
10-26-2009 08:16:03
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The contents of this article is licensed from www.wikipedia.org under the GNU Free Documentation License. Click here to see the transparent copy and copyright details