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Chlorphenamine
(Redirected from Chlorpheniramine maleate)
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| (3RS)-3-(4-chlorophenyl)-N,N-dimethyl- 3-(pyridin-2-yl)propan-1-amine | |
| CAS number 132-22-9 | ATC code ? |
| Chemical formula | C16H19ClN2 |
| Molecular weight | 274.8 |
| Bioavailability | 25-50% |
| Metabolism | hepatic |
| Elimination half-life | 6.3-23.1 hours |
| Excretion | renal |
| Pregnancy category | Category A (Australia) |
| Legal status | Schedule 3 (Australia) |
| Routes of administration | oral |
Chlorphenamine (INN) or chlorpheniramine (USAN, former BAN), commonly marketed as its salt chlorphenamine maleate (CPM), is first-generation antihistamine used in the prevention of the symptoms of allergic conditions such as rhinitis and urticaria.
CPM is one of the main ingredients in many OTC allergy medications, such as Coricidin Cough & Cold (or CCC). Many people use Coricidin recreationally for the dextromethorphan content; however, this is strongly recommended against. In high doses, chlorpheniramine maleate can cause severe allergic reactions and has been linked to at least twelve deaths in the United States.
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10-26-2009 08:16:03
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The contents of this article is licensed from www.wikipedia.org under the GNU Free Documentation License. Click here to see the transparent copy and copyright details