Sir Cyril Wyche (1632 - ?1707) was an English lawyer and politician.

He was born in Constantinople, Turkey, where his father, Sir Peter Wyche, was the English Ambassador. He was educated at Christ Church, Oxford with BA in 1653. He received his MA in 1655 and his DCL in 1665. Between the time he received his MA and his DCL he was knighted (1660). This is so close in time to the English Restoration that he was almost certainly a royalist, and may have served in the military for the royalist cause.

He was an original member of the Royal Society and served as President from 1683-1684. He joined the bar in 1670 and became the Secretary to the Lieutenancy of Ireland in 1692. He was a Member of Parliament for several districts at different times, (MP for Callington, Cornwall (1661-1678), for East Grinstead (1681), for Saltash (1685-1687), and for Preston (1702-1705) From the Sackler Archive of Fellows of the Royal Society.

He married Mary, daughter of George Evelyn of Wootton and niece of John Evelyn, the diarist. Around 1690 he purchased Hockwold Hall (then called The Poynings) at Hockwold cum Wilton, Norfolk. He died there and a monument to him can be found in the church of St. Peter in Hockwold.

|- style="text-align: center;" | width="30%" |Preceded by:
John Davis | width="40%" style="text-align: center;" |Chief Secretary for Ireland
1692–1693 | width="30%" |Succeeded by:
Sir Richard Aldworth

See also

• Presidents of the Royal Society