Science Fair Project Encyclopedia
DNA ligase
In molecular biology, DNA ligase is an enzyme that repairs broken DNA strands. DNA ligase (EC 6.5.1.1) is a particular type of enzyme that can form covalent phosphodiester bonds and ligate or connect (broken) DNA strands.
An example of how a ligase works (with sticky ends):
5'-AGTCTGATCTGACT GATGCGTATGCTAGTGCT-3' 3'-TCAGACTAGACTGACTACG CATACGATCACGA-5'
becomes
5'-AGTCTGATCTGACTGATGCGTATGCTAGTGCT-3' 3'-TCAGACTAGACTGACTACGCATACGATCACGA-5'
External links
03-10-2013 05:06:04
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The contents of this article is licensed from www.wikipedia.org under the GNU Free Documentation License. Click here to see the transparent copy and copyright details


