David Arquette (born September 8, 1971 in Winchester, Virginia) is an American actor from something of a Hollywood dynasty. His sisters Patricia and Rosanna, and brothers Alexis and Richmond are all actors. Their father was Lewis Arquette , and his father was comic actor Cliff Arquette, best remembered for his "Charlie Weaver" character, a fixture on the original Hollywood Squares.

David achieved his biggest success in the horror trilogy Scream (1996), Scream 2 (1998) and Scream 3 (2000) as Deputy Dewey. He also met his older wife Courteney Cox on the set, and married her in 1999. Their first child, a daughter, was born in 2004. They have also appeared together in a Coke ad on TV in 2003.

He supported John Kerry during the 2004 election.

Arquette is much disliked by professional wrestling fans, after he "won" the WCW World Heavyweight Title in 2000 in an effort to promote his wrestling-based movie, Ready to Rumble . The angle was hugely unpopular; even Arquette himself reportedly thought it was a bad idea, before being convinced to do the stunt.

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