Desinicization (que zhong hua, de + sinicization, meaning making non-Chinese) is a term which appeared within the political vocabulary of the Republic of China on Taiwan in 2001. It is mainly used by groups which support Chinese reunification to describe what they are opposed to, and to distinguish it from the Taiwanese localization movement.

The term exists to emphasize that pro-unification groups are not opposed to the development of a Taiwanese identity or local symbols such as language, but are opposed to viewing such an identity and symbols as separate from a broader Chinese identity.

The Shan drug-lord Khun-Sa of Myanmar is also an example of desinicization; he belongs to the second generation of Kuomintang officers who sought refuge in the Shan State.

Many Taiwanese localization movement supporters in Taiwan also take recent Seoul city mayor's move to change Seoul city's Chinese official name from 漢城 (read as Hancheng in Chinese, Hanseong in Korean) to Shou'er (首爾) in 2005 as a model of desinicization.

The Dungans of Kyrgyzstan represent a less conscious process of desinicization, in the course of which (300 years since early Qing) a Hui population became alienated from the literary tradition and local culture of Shaanxi and Gansu.

The notion of desinicization has also been applied to Chinese Americans with the pejorative term banana (i.e. yellow on the outside, white on the inside.)