Edward Macnaghten, Baron Macnaghten, GCB, GCMG (February 3, 1830) - (February 17, 1913) was an British lawyer and politician. He was born the second son of Sir Edmund Charles Workman-Macnaghten , 2nd Baronet, and educated at Queen's College, Belfast, and Trinity College, Cambridge, graduating BA in 1852.

After being called to the bar in 1857, Macnaghten built up a successful practice and became Queen's Counsel in 1880. That same year he was elected to the House of Commons as Conservative Member of Parliament for County Antrim, exchanging this seat five years later for that of North Antrim. Having declined the offers of a judgeship from Gladstone and the Home Secretaryship from the Conservatives, he was in 1887 appointed a Lord of Appeal in Ordinary, becoming a life peer as Baron Macnaghten, of Runkerry (his home near Bushmills) in the County of Antrim.

Lord Macnaghten was made a Knight Grand Cross of the Order of St Michael and St George in 1902 and a Knight Grand Cross of the Order of the Bath in the 1911 coronation honours of George V. He also succeeded his elder brother, Francis, as fourth Baronet in the latter year.

He died of pneumonia in 1913 at his home in Kensington, London, and was buried at Bushmills.