Eutropius (d. 399) was a fourth century Eastern Roman official.

He began his career as a eunuch in the palace of Theodosius I. After Theodosius' death in 395 he successfully arranged the marriage of the new emperor, Arcadius, to Eudoxia, having blocked an attempt by Arcadius' chief minister, Rufinus, to marry the young and weak-willed emperor to his daughter. After Rufinus' assassination that same year, Eutropius rose in importance in the imperial court, and he soon became Arcadius' closest advisor. His ascension to power was assisted by his defeat of a Hun invasion in 398. The next year he became the first eunuch to be appointed a consul. He made enemies of both Gaïnas the leader of the imperial army's Gothic mercenaries, and Eudoxia, the empress he had created, and these two powerful figures engineered his downfall the same year he became a consul.

After Eutropius fall from power, St. John Chrysostom's pleas kept him alive for a time, but he was eventually executed before the year ended.

During his rise to the consulship, Eutropius earned the emnity of the people due to his reputation for cruelty and greed. He may also have played a role in the assassination of his predecessor Rufinus.