Extreme Ghostbusters (1997) is a more recent (but short-lived) incarnation/sequel of The Real Ghostbusters cartoon series. Extreme Ghostbusters featured a new team of younger Ghostbusters led by veteran Ghostbuster Egon Spengler and secretary Janine Melnitz. Extreme Ghostbusters appared to be very politically correct when it came to chosing the new Ghostbusters. The new Ghostbusters were Roland Jackson, who replaced Winston Zeddemore as the token African-American Ghostbuster, Garrett Miller, who was wheelchair-bound, Eduardo Rivera, who seemed to be meant as a Latino variation of Peter Venkman, and Kylie Griffin, who was a Goth girl.

The theme music for Extreme Ghostbusters took a unique twist on the familar Ray Parker Jr. theme. The new theme was basically a heavy metal inspired variation of the original Ghostbusters theme song.

Perhaps the most notable episode of Extreme Ghostbusters was the two part episode entitled "Back in the Saddle." In that episode, all of the original Ghostbusters team up with their successors for an adventure. Dave Coulier (voice of Peter Venkman), Buster Jones (voice of Winston Zeddemore), and Frank Welker (voice of Ray Stantz) reprised their roles from The Real Ghostbusters.