Science Fair Project Encyclopedia
Ezetimibe
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| (3R,4S)-1-(4-fluorophenyl)- 3-((3S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4- (4-hydroxyphenyl)-2-azetidinone | |
| CAS number 163222-33-1 | ATC code C10AX09 |
| Chemical formula | CH21F2NO3 |
| Molecular weight | ? |
| Bioavailability | 35-65% |
| Metabolism | Glucuronidation up to 90% |
| Elimination half life | ? |
| Excretion | Biliary (78%) and renal (11%) |
| Pregnancy category | ? |
| Legal status | ? |
| Delivery | Oral tablets 5, 10, 20 mg |
Ezetimibe (Zetia®) is an anti-hyperlipidemic medication. It acts by decreasing cholesterol absorption in the intestine. It is used together with statins (Vytorin®) to help lower cholesterol in patients who cannot be controlled on statins alone.
10-26-2009 08:16:03
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The contents of this article is licensed from www.wikipedia.org under the GNU Free Documentation License. Click here to see the transparent copy and copyright details