The Friedrichstraße (pronounced in IPA) (Frederick Street) is a major shopping street in (east) central Berlin. It runs from the northern part of old Mitte (north of which it is called Chausseestraße) to the Hallesches Tor in the district of Kreuzberg. Due to its north-southerly direction, it forms important junctions with the east-western axes, most notably with Leipziger Straße and Unter den Linden. The U6 subway runs underneath.

Many of the finest fashion brands have an outlet on Friedrichstraße. It has also been a playground for creators of modern architecture during the general refurbishment period in the 1990s.

Despite being of such critical economic importance, Friedrichstraße is remarkably narrow, causing regular traffic jams.

The famous 20th century architect, Ludwig Mies van der Rohe, once created a charcoal image of the Friederichstrasse, idealizing it as a street with the potential for all the hopes and dreams that the early 20th century envisioned for the future.