George Talbot, 6th Earl of Shrewsbury (1528–18 November 1590) was an English statesman during the 16th century.

Talbot was the only son of Francis Talbot, 5th Earl of Shrewsbury , a somewhat obscure nobleman. By virtue of the hereditary peerage, George was known by the courtesy title Baron Furnivall from birth until 1560, the year of his father's death. In that year, he inherited the Earldom of Shrewsbury, the Barony of Furnivall and the position of Justice in Eyre, which had been passed down the family for a few generations. One year later, he was created a Knight of the Garter, and in 1567, he married Bess of Hardwick. Although their two eldest children (from previous marriages) married each other, their marriage was marred by Lord Shrewsbury's selection as the keeper of Mary, Queen of Scots (who was effectively exiled by Queen Elizabeth I).

Meanwhile, in 1571, Lord Shrewsbury was appointed Lord High Steward (the premier Great Office of State) for the trial of Thomas Howard, 4th Duke of Norfolk (regarding the Ridolfi plot). Finally, in 1572, Lord Shrewsbury was appointed Earl Marshal, a position that he held (along with the aforementioned position of Justice in Eyre) until his death in 1590. Upon his death, his eldest son (from the marriage with Gertrude Manners ) inherited the earldom.