Gregory II was patriarch of Constantinople between 1283-1289.

He was born in 1241 in Lapithos, Cyprus and his name was originally George. His parents were middle class but of noble origin. He moved to Nicosia as a teenager seeking further education. Not satisfied by the level of education provided by local teachers in Greek, he became a student at a Latin school (available then as Cyprus was a crusader Kingdom). He had difficulty learning Latin and thus got only a superficial knowledge of grammar and Aristotle's Logic.

Still determined to get a decent education, he got on a ship to Ptolemais, Palestine, where he arrived after three days. From there he travelled to Anaea in Asia Minor and finally made it to Ephesos. He had heard a lot about the scholar Blemmydes but was dissapointed by him and moved to Nicaea were he studied with Acropolites. With the recapture of Constantinople by Nicaean forces in 1261, he moved there.

He became patriarch in 1283. He wrote collections of proverbs and his autobiography. He died in 1290.