Guido Molinari (October 12, 1933 - February 21, 2004) was a Canadian artist, known for his abstract paintings.

Molinari was born in Montreal. He began painting at age 13, and his existentialist approach to art was formed during a bout with tuberculosis at age 16, during which he read Nietzsche, Sartre, Piaget, and Camus. He studied at the École des beaux-arts de Montréal and the Montreal Museum of Fine Arts .

He practised abstraction in New York, inspired by Jackson Pollock, then returned to Montreal where he produced some of the finest pieces of his career. He married Fernande Saint-Martin in 1958. He won a Guggenheim Fellowship in 1967, was made an Officer of the Order of Canada in 1971, and won the Prix du Québec in 1980.

His work is known for its focus on modular and contrasting colours, shapes, and lines. It is exhibited worldwide, including the National Gallery of Canada, the Musée d'art contemporain de Montréal , and the Guggenheim Museum and Museum of Modern Art in New York.

He died in Montreal.