Lipscani is a street and an district of Bucharest, Romania, which in the Middle Ages was the most important commercial center of Bucharest and the whole Wallachia.

It was named after Leipzig ("Lipsca" in Romanian), as that was the origin of many of the wares that could be found on this street. All trades were found there, including goldsmiths, hatters, shoemakers, tanners, saddlemakers, etc., many crafts having their own street: even nowadays, the nearby streets bear the name of a trade (Blănari = Tanners street, Şelari = Saddlemakers street, etc).

During the Communist period, the whole region was scheduled to be demolished. Many of the buildings became neglected, and even nowadays many of them have not been restored for a long time.

Nearby is also located the old Princiary Court of Vlad Ţepeş.