The following list contains all the Popes who have held sway over the Coptic Orthodox Church since the Council of Chalcedon.

For the earlier Patriarchs of Alexandria prior to the schism, see List of Patriarchs of Alexandria; for the patriarchs of the Eastern Orthodox church from which the Coptic Church split, see List of Orthodox Patriarchs of Alexandria.

• Dioscorus I (444–457)
• Timothy II (457–477)
• Peter III (477–489)
• Athanasius II (489–496)
• John I (496–505)
• John II (505–516)
• Dioscorus II (516–517)
• Timothy III (517–535)
• Theodosius I (535–566)
• Dorotheos (565–580)
• Damian (578–607)
• Anastasius (607–619)
• Andronicus (619–665)
• Agatho (665–681)
• John III (681–689)
• Isaac (689–692)
• Simeon I (692–700)
• Alexander II (702–729)
• Cosmas I (729–730)
• Theodorus II (730–742)
• Michael I (743–767)
• Mina I (767–775)
• John IV (776–799)
• Mark II (799–819)
• Jacob (819–830)
• Simeon II (830)
• Joseph I (831–849)
• Khail II (849–851)
• Cosmas II (851–858)
• Shenouda I (859–880)
• Khail III (880–907)
• Gabriel I (910–921)
• Cosmas III (921–933)
• Macarius I (933–953)
• Theophilus (953–956)
• Mina II (956–974)
• Abraham (975–978)
• Philotheos (979–1003)
• Zacharias (1004–1032)
• Shenouda II (1032–1046)
• Christosolos (1047–1077)
• Cyril II (1078–1092)
• Michael IV (1092–1102)
• Gabriel II (1102–1128)
• Michael V (1145–1146)
• John V (1146–1166)
• Mark III (1166–1189)
• John VI (1189–1216)
• Cyril III (1235–1243)
• Athanasius (1250–1261)
• John VII (1261–1268)
• Gabriel III (1268–1271)
• John VII (restored) (1271–1293)
• Theodosius III (1300–1320)
• John IX (1320–1327)
• Benjamin II (1327–1339)
• Peter V (1340–1348)
• Mark IV (1348–1363)
• John X (1363–1369)
• Gabriel IV (1370–1378)
• Matthew I (1378–1408)
• Gabriel V (1408–1427)
• John XI (1428–1453)
• Matthew II (1453–1466)
• Gabriel VI (1466–1475)
• Michael IV (1475–1477)
• John XII (1480–1483)
• John XIII (1483–1524)
• Gabriel VII (1526–1569)
• John XIV (1573–1589)
• Gabriel VIII (1590–1601)
• Mark V (1610–1621)
• John XV (1621–1631)
• Matthew III (1631–1645)
• Mark VI (1645–1660)
• Matthew IV (1660–1676)
• John XVI (1676–1718)
• Peter VI (1718–1726)
• John XVII (1727–1745)
• Mark VIII (1745–1770)
• John XVIII (1770–1797)
• Mark IX (1797–1810)
• Peter VII (1810–1854)
• Cyril IV (1854–1861)
• Demetrius II (1862–1870)
• Cyril V (1874–1928)
• John XIX (1929–1942)
• Macarius III (1942–1944)
• Joseph II (1946–1956)
• Cyril VI (1959–1971)
• Shenouda III (1971–present)