This is a list of cartoon, comic or animated characters who appear together as a pair or are pitched against each other. For a complete listing of pairs, see Lists of pairs. For a list sorted by name, see List of pairs by name.

A-Z

• Archie and Jughead: Archie Comics characters
• Asterix and Obelix: French comics characters
• Augie Doggie and Doggie Daddy: Hanna-Barbera animated cartoon
• Babs and Buster Bunny: from the Warner Bros. animated television series Tiny Toon Adventures
• Bart and Lisa Simpson: animated characters from The Simpsons series
• Batman and Robin: DC Comics superheroes, also adapted into other media
• Beany and Cecil: television characters
• Beavis and Butthead: MTV animated cartoon
• Beauty and the Beast: various adaptations, notably the Disney animated cartoon
• Billy the Cat and Katie: comic strip
• Bob and Margaret: from the Bob and Margaret animated cartoon series
• Bully Beef and Chips: comic strip
• Buster Brown and Tige: comic strip creations of Richard F. Outcault
• Calvin and Hobbes: comic strip creations of Bill Watterson
• Casper and Wendy: Harvey Comics characters
• Cloak and Dagger: Marvel Comics superheroes
• Charlie Brown and Snoopy: comic strip creations of Charles M. Schulz
• Chip and Dale: Disney animated cartoons
• Corneil and Bernie
• Cosmo and Wanda: from the Nickelodeon animated television series The Fairly OddParents
• Cow and Chicken: Cartoon Network animated cartoon
• Cuddles and Dimples: comic strip
• Dastardly and Muttley: animated characters from Hanna-Barbera's Wacky Races, and later their own series.
• Dennis the Menace and Gnasher: comic strip
• Dexter and Dee Dee: from the Cartoon Network animated television series Dexter's Laboratory
• Earl and Mooch: Mutts Comics, notably comic strip creations of Patrick McDonnell
• Fievel and Tanya Mousekewitz: various adaptions, notably the Universal Studios animated cartoon
• Fred Flintstone and Barney Rubble: various adaptations, notably the Hanna-Barbera animated cartoon
• Gnasher and Gnipper: comic strip
• Gumby and Pokey: claymation television series
• Hawk and Dove: DC Comics superheroes
• Herman and Katnip: Harvey Comics characters
• Hi and Lois: comic strip
• Hubie and Bertie: characters in the Warner Bros.' Looney Tunes and Merrie Melodies series of animated cartoons
• Inspector Horse and Jocky: comic strip
• Itchy and Scratchy: fictional animated cartoon characters in The Simpsons
• Jay and Silent Bob: recurring characters in the New Jersey films by Kevin Smith
• Jonathan Gabriel and Tycho Brahe: characters in a long-running web comic concerning the video game industry
• Kaput and Zösky
• Kevin and Kell: webcomic
• Krazy and Ignatz: comic strip
• Lady and the Tramp: Disney animated cartoon
• Laurel and Hardy: animated cartoon based on the actors' characters
• Lilo and Stitch: Disney animated cartoon
• Linus and Lucy: comic strip creations of Charles M. Schulz
• Mandrake the Magician and Lothar: comic strip magician and strong man
• Marc Antony and Pussyfoot: characters in the Warner Bros.' Looney Tunes and Merrie Melodies series of animated cartoons
• Max and Moritz
• Mickey Mouse and Pluto: from the Disney animated series Mickey Mouse
• Modesty Blaise and Willie Garvin: comic strip
• Morty and Ferdie Fieldmouse: Mickey's nephews from Disney animated cartoons
• Mutt and Jeff: comic strip creations of Harry Conway "Bud" Fisher
• Nancy and Sluggo: comic strip creations of Ernie Bushmiller
• Norbert and Daggett: from the Nickelodeon animated television series The Angry Beavers
• The Phantom and Devil: comic hero and a mountain wolf
• Pinky and the Brain: animated cartoon characters in Warner Bros.' Animaniacs and later their own series
• Pixie and Dixie: Hanna-Barbera animated cartoon: (not forgetting Mr. Jinks).
• Ren and Stimpy: MTV animated cartoon
• Rocky and Bullwinkle: animated cartoon
• Rocky and Mugsy: characters in the Warner Bros.' Looney Tunes and Merrie Melodies series of animated cartoons
• Rose and Thorn : DC Comics superheroes
• Ruff and Reddy : Hanna-Barbera animated cartoon
• Sam and Max: animated cartoon
• Sam Sheepdog and Ralph Wolf: characters in the Warner Bros' Looney Tunes and Merrie Melodies series of animated cartoons
• Scooby-Doo and Shaggy: Hanna-Barbera animated cartoon
• Spike the Bulldog and Chester the Terrier: characters in the Warner Bros.' Looney Tunes and Merrie Melodies series of animated cartoons
• Thomson and Thompson (Dupont et Dupond in the original Belgian): twin-like detectives in the Tintin comic series
• Tintin and Snowy (Tintin et Milou in the original Belgian): world travelers in the Tintin comic series
• Tom and Jerry: animated cartoon
• Tommy Tortoise and Moe Hare: Harvey Comics characters
• Triangle and Robert: webcomic
• Wallace and Gromit: claymation films, notably creations of Nick Park
• Wile E. Coyote and the Road Runner: Warner Bros. animated cartoon
• Yogi Bear and Boo Boo: Hanna-Barbera animated cartoon

See also

• List of comic books
• List of comic strips
• Archive of fictional things