Lough Erne (Irish: Loch Éirne) refers to two lakes in Ireland, situated along the River Erne . This waterway is found in the North-west of Ireland, with the lakes located in County Fermanagh, Northern Ireland. The river flows in a north-westly direction, beginning by flowing north, and then curving west into the Atlantic. The southern-most lake is further up the river and so is named Upper Lough Erne. The northern lake is Lower Lough Erne.

A canal exists between the upper end of the River Shannon and the River Erne, allowing boat movements from the Shannon estuary in south-west Ireland, all the way through the midlands of the country, and across to the Northwest and out to the Atlantic again.

Lough Erne is a particularly scenic waterway in Ireland, it is renowned for the beautiful setting. The area is also popular for fishing. The town of Enniskillen in Northern Ireland is situated next to the lakes.

The Annals of Ulster were written in the late 15th century on Belle Isle on Lough Erne.

Islands

The lakes contain many small islands, and peninsulas called "islands" because of the highly convoluted shoreline. Those in the lower lake include Boa Island, Cleenishmeen Island, Crevinishaughy Island, Cruninish Island, Devenish Island, Ely Island, Horse Island, Inish Doney, Inish Fovar, Inish Lougher, Inish More, Inishmacsaint, Inishmakill, Lusty Beg Island, Lusty More Island, White Island. Those in the upper lake include Bleanish Island, Dernish Island, Inishcorkish, Inishcrevan, Inishfendra, Inishleague, Inishlught, Inishturk, Killygowan Island, Naan Island, Trannish.