Science Fair Project Encyclopedia
MARCKS protein
MARCKS proteins (myristoylated alanine-rich C-kinase substrate) play important roles in cell mobility , secretion, transmembrane transport , and regulation of the cell cycle. All are protein kinases.
They are acidic proteins with high proportions of alanine, glycine, proline, and glutamic acid. They are membrane-bound through a lipid anchor at the N-terminus. They are regulated by Ca2+/calmodulin and protein kinase C. In their phosphorylated form, they bind to actin filaments, causing them to crosslink.
10-26-2009 08:16:03
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The contents of this article is licensed from www.wikipedia.org under the GNU Free Documentation License. Click here to see the transparent copy and copyright details