Aisha was never a bitter enemy of Ali. The truth of the matter is that after the assassination of the third caliph, Uthman ibn Affan, there was a difference of opinion on what to do with the killers.

Aisha along with some of Muhammad's friends belived that the killers must be punished emedietly. While Ali along with other companions of Muhammad, said that first we must stablize the Muslim nation after the horrific events of Uthan's assassination..... and then punish the killers.

Ali had his army, and Aisha had hers. They first got there armies together to negotiate what to do with the difficult situation. But then one of the men in Aisha's army named Talha (also a very beloved companion of Muhammad), Was stuck by an arrow in his leg by a non-muslim hoping that by killing him, he can start a civil war. And he did.

Aisha's army blamed Ali's army and then the war civil war started killing many people. The armies met together to negotiate but because an unknown person killed Talha , people misinterprited and thought there was a feud between the Prophet's most beloved wife, and the Prophet's dearly beloved cusin and son-in-law.