Neisseria gonorrhoeae is a species of Gram-negative (see also Gram Stain ) bacteria responsible for the disease gonorrhoea. Neisseria species of bacteria are highly fastidious gram negative cocci, that is, they require special nutrients to survive. These cocci appear microscopically in pairs, which are also known as diplococci. Gonnorrhoea is a sexually transmitted disease. Symptoms include a purulent (or pus-like) discharge from the genitals which may be foul smelling, and a burning sensation during urination. Neisseria is usually isolated on a Modified Thayer-Martin culture plate . This plate has antibiotics and nutrients which not only facilitate the growth of Neisseria species, but inhibit the growth of Gram-positive organisms and most bacilli. Further testing to differentiate the species usually includes an oxidase test which will be positive for Neiserria gonorrhoeae, and testing with the carbohydrates lactose, sucrose, and glucose. N. gonnorhoeae will only ferment (that is, utilize) the glucose. Treatment for Neisseria gonnorhoeae usually involves antibiotics inserted into the gentiallia through a probe.