Science Fair Project Encyclopedia
(3R,4R,5S)-4-acetylamino-5-amino-3- (1-ethylpropoxy)-1-cyclohexene-1-carboxylic acid ethyl ester
|Metabolism||hepatic, to GS4071|
|Half life||6-10 hours|
|Pregnancy category||B1 (Australia)|
Oseltamivir is a neuraminidase inhibitor used in the treatment of and prophylaxis of both influenza A and influenza B. Oseltamivir was the first orally active neuraminidase inhibitor commercially developed. It was developed by Gilead Sciences and is currently marketed by Hoffman La Roche under the trade name Tamiflu®.
Oseltamivir is a prodrug, usually administered as oseltamivir phosphate, with the drug being converted heptically to the active metabolite GS4071 in vivo.
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