Paterson Inlet is a large natural harbour in the eastern coast of Stewart Island, New Zealand.

Much of the coast of the inlet is unspoilt forest. Maori settled here at a locale known as The Neck, a long peninsula which extends across the mouth of the inlet from the south coast. The only town on Stewart Island, Oban is located on the north coast of the inlet, close to its mouth. In earlier times, the inlet was used as a base for whaling.

Paterson Inlet has three main arms. North Arm and South West Arm lie at the upper reaches of the inlet, 15 kilometres from its mouth. Big Glory Bay, the third arm of the inlet, lies behind The Neck in the southeast of the inlet. The inlet drains the Rakeahua and Freshwater Rivers , the latter of which drains a large swampy valley that covers much of the northern part of the island.

Several islands lie in the inlet, notably Ulva Island and Native Island .

In June 2004 the government announced that Paterson Inlet will become a mataitai to be known as Te Whaka a Te Wera Mätaitai Reserve. [1]