Science Fair Project Encyclopedia
Pharmacophore
A pharmacophore is a three-dimensional substructure of a molecule that carries (phoros) the essential features responsible for a drug's (pharmacon) biological activity. Alternatively described as an ensemble of interactive functional groups with a defined geometry. Basically, one tries to talk the protein language by finding the "structural and chemical complementaries" (aka pharmacophore hypothesis) to target receptors.
10-26-2009 08:16:03
The contents of this article is licensed from www.wikipedia.org under the GNU Free Documentation License. Click here to see the transparent copy and copyright details
The contents of this article is licensed from www.wikipedia.org under the GNU Free Documentation License. Click here to see the transparent copy and copyright details