The Pomona Freeway is the assigned name of the majority of California State Highway 60 (CA/SR-60) between its western terminus at the East Los Angeles Interchange complex and its junction with the Riverside Freeway, California State Highway 91 (CA/SR-91) and Interstate 215 (California) (I-215) in Riverside. The freeway itself continues east beyond this interchange but does so as the Moreno Valley Freeway.

It traverses through Los Angeles, San Bernardino, and Riverside counties. As it passes through many of Los Angeles' east side suburbs in southern San Gabriel and Pomona valleys, it is a major transportation corridor. For the majority of its length it is generally parallel to, and south of, the San Bernardino Freeway, Interstate 10 (I-10), and generally parallel to, and north of, the Riverside Freeway. Traffic congestion is excacerbated by the rapid population growth and, therefore, residential, commercial, and industrial development in the inland communities known informally as the Inland Empire. In particular, it has become increasingly clogged of late with shipping container-laden trucks travelling from the ports of Los Angeles and Long Beach to rail yards and warehouses in the Inland Empire.

Cities/Communities along the Pomona Freeway (west to east)

• Boyle Heights
• East Los Angeles
• Monterey Park
• Montebello
• Rosemead
• South El Monte
• Industry
• Diamond Bar
• Pomona
• Chino
• Ontario
• Rubidoux
• Riverside

Major Highways/Freeways that intersect with the Pomona Freeway (west to east)

• Santa Monica Freeway - Interstate 10 (I-10) at the East Los Angeles Interchange complex

at 34° 01' 46"N, 118° 13' 29"W

• Santa Ana Freeway - Interstate 5 (I-5) at the East Los Angeles Interchange complex

at 34° 01' 45"N, 118° 12' 50"W

• Long Beach Freeway - Interstate 710 (I-710) in East Los Angeles

at 34° 02' 08"N, 118° 10' 12"W

• Rosemead Boulevard (surface street) - California State Highway 19 (CA/SR-19) in near South El Monte

at 34° 02' 28"N, 118° 03' 51"W

• San Gabriel River Freeway - Interstate 605 (I-605) in unincorporated Los Angeles County

at 34° 02' 02"N, 118° 01' 38"W

• Orange Freeway - California State Highway 57 (CA/SR-57) in Diamond Bar

at 34° 01' 20"N, 117° 48' 49"W and 34° 00' 06"N, 117° 50' 11"W

• Chino Valley Freeway - California State Highway 71 (CA/SR-71) in Pomona

at 34° 01' 24"N, 117° 44' 52"W

• Euclid Avenue (surface street) - California State Highway 83 (CA/SR-83) in Ontario

at 34° 01' 49"N, 117° 39' 03"W

• Ontario Freeway - Interstate 15 in unincorporated Riverside County

at 34° 01' 18"N, 117° 33' 01"W

• Riverside Freeway - California State Highway 91 in Riverside

at 33° 59' 36"N, 117° 21' 26"W