Renée of France (October 25, 1510 - June 12, 1574), also known as Renée de France and Renata di Francia.

Renée was born on October 25, 1510 in the Chateau de Blois, Blois, France and was the second daughter of Louis XII, King of France and Anne, Duchess of Brittany. Her mother, who had always fought fiercely to keep Brittany independent of the French crown, tried to will the duchy to Renée, but her father King Louis ignored this and instead granted Brittany to his successor, Francis I, King of France.

In return for renouncing her claims to the duchy of Brittany, Renée was granted the duchy of Chartres by Francis I, King of France. As a child, one of her companions was the young Anne Boleyn, who Renee always remembered with kindness and affection.

Renée was married in 1528 to Ercole II, Duke of Ferrara , who succeeded to his dukedom in 1534.

1. Alfonso II, Duke of Ferrara (November 22, 1533-1597)
2. Anna d'Este (November 16, 1531-1607), married (1) Francis, Duke of Guise; (2) Jacques de Savoie, 2nd Duc de Nemours
3. Lucrezia Maria d'Este (December 16, 1535-1598), married Francesco Maria II della Rovere, Duke of Urbino
4. Luigi d'Este, Bishop of Ferrara, Archbishop of Auch (December 21, 1538-1586)

Renee was widowed in 1559. As a result of being of bad terms with her son, Alfonso II, Duke of Ferrara , she returned to France in 1560 and settled in Montargis , where she then died on June 12, 1574.