Shimazu Takahisa (島津貴久; 1514-July 15, 1571) was a daimyo during Sengoku period. He is the fifteenth of Shimazu clan and the son of Shimazu Tadayoshi.

On 1526, Takahisa was adopted as a son of Shimazu Katsuhisa to become the head of the clan. He successfully united the clan again winning battles against Satsuma branch of the Shimazu clan. He launched series of campaigns to reclaim three provinces, Satsuma, Osumi, and Hyuga which made some starts but it would be up to the next generation to succesfully reclaiming them. He nurtured such future leaders like Shimazu Yoshihisa, Shimazu Yoshihiro, Shimazu Toshihisa and Shimazu Iehisa who would make the Shimazu clan take over the entire island of Kyushu.

Takahisa actively promoted relationships with foreign person and countries. On 1549, he granted Francis Xavier, the protection to spread Christianity in his domain. He also held a diplomatic relationship with Ryukyu Kingdom