Sister, Sister is the name of several works.

1982 TV movie

Sister, Sister is a 1982 TV movie based on a Maya Angelou story, starring Diahann Carroll, Irene Cara and Rosalind Cash as three sisters with moral and personal conflicts trying to maintain a household after the death of their father. (IMDb listing)

1987 movie

Sister, Sister is a 1987 thriller starring Eric Stoltz, Jennifer Jason Leigh, and Judith Ivey . The girls run a guesthouse in the Louisiana swamp, where the secrets of their dark past will eventually come to light. (IMDb listing)

1994-1999 TV series

Sister, Sister is a television sitcom about two African American girls who have found out that they are twin sisters.

The show stars Tia and Tamera Mowry as the twins, Tim Reid and Jackée Harry as their adoptive parents, and Marques Houston as their annoying neighbor, Roger. Sister, Sister also features occasional appearances by Brittany Murphy as their best friend. (IMDb listing)

The first season of Sister, Sister aired on ABC. Subsequent seasons aired on The WB, and reruns of the show are today seen on The Disney Channel.