Sisters was the name of a television drama which aired on NBC from 1991 to 1996. The show revolved around the Reed sisters who all lived in Winnetka, Illinois.

The oldest sister was Alex, who was played by Swoosie Kurtz. She was very protective of her younger siblings and intervened when there was a crisis. She filled the mother role for the group, which added to the safety of the family dynamic as their mother, Bea (played by Elizabeth Hoffman ) was seen frequently. Alex and Bea watched over Teddy, Georgie, and Frankie, who were played by Sela Ward, Patricia Kalember , and Julianne Phillips, respectively.

Later, the sisters became aware of a fifth "sister", who was the love child of an affair the Reed father had with another woman. This fifth sister, Charley (played by Jo Anderson and then by Sheila Kelley ) factored into storylines starting in 1994.

The show was created by Ron Cowen and Daniel Lipman , who went on to adapt Queer as Folk for the American market.