Thomas Pryor Gore (December 10, 1870 - March 16, 1949) was a Democratic politician. He was a U.S. Senator from Oklahoma from 1907 until 1921 and from 1931 until 1937. He is notable for being totally blind as well as for being the maternal grandfather of author Gore Vidal.

He became blind as a child, but did not give up his dream of becoming a senator. In 1907 he was elected to the Senate as one of the first two senators from the new state of Oklahoma. He was reelected in 1908 and 1914 but defeated in 1920. He was known as a member of the progressive wing of the Democratic Party, who worked with Republicans such as Robert La Follette. He was to a large extent no different from any other politician because of his blindness, but there were problems, as La Follette recounts an example in his memoirs when, during a filibuster, Gore did not realize that the senator who was to take over speaking for him had left the room, and the filibuster failed because he did not continue to speak.

He is also noted as being the author of a bill placed before the United States Senate during the early stages of World War I which encouraged American citizens not travel aboard belligerent merchant vessels. The merchant vessels were under threat of attack by German U-boats and the Senator felt the loss of American lives upon these boats threatened official American neutrality at the time.

Gore was reelected in 1930 to the Senate. When Franklin Roosevelt first took office as president, Gore at first supported his New Deal, but later feuded with him.

He married Nina Belle Kay , a Texas plantation owner's daughter, in 1900. They had two children, Nina Gore (1903-1978), the mother of Gore Vidal and Thomas Notley Gore (1910-).