Thomas Macdonough (23 December 1783 - 10 November 1825), was a U.S. naval officer.

Commodore Macdonough was born 23 December 1783 in The Trap (now Macdonough ), Delaware. He was appointed midshipman 5 February 1800 and participated with distinction in operations against Tripoli, 1803‑04, serving on Philadelphia before her capture and volunteering for the dash into Tripoli Harbor with Decatur to burn the captured vessel.

During the War of 1812, he commanded the United States Squadron on Lake Champlain. In 1814 on Lake Champlain and Plattsburgh (September 11), a US squadron under Macdonough defeated the British under George Downie . In denying control of the lake to the British, Macdonough’s victory forced the invading army to retire to Canada, and left no grounds for British territorial claims in the area at the Ghent peace conference.

Honored by Congress with promotion to captain, he served as Commandant, Portsmouth Navy Yard 1815‑1818, before assuming command of Guerriere and taking up station in the Mediterranean. He sailed to the Mediterranean again in 1824 as commanding officer of Constitution, but because of poor health was relieved 14 October 1825 at his own request. He departed for home in Edwin, but died at sea 10 November 1825 and was buried in Middletown, Connecticut.

He was later honoured a stamp.

Several ships of the Navy have been named USS Macdonough in his honor.