Vertigo is a comic book supervillainess in the Marvel Universe and one of the Marauders, and an enemy of the X-Men.

Vertigo is a native of the Savage Land and obtained superhuman powers at a young age by genetic engineering. Her powers enable her to render a person severely dizzy and even unconscious. She became a member of a group of mutants known as the Savage Land Mutates, and in this group she first battled the X-Men.

Later, she joined the Marauders, a group of mutants working as assassins for a mad scientist named Mr. Sinister. The scientist wanted his assassins to destroy a large community of mutants, known as the Morlocks, who lived under New York City. They did succeed in annihilating a large number of the underground mutants. While the Marauders were accomplishing this, they also clashed with the X-Men, Thor, X-Factor, and Power Pack.

Soon after this, Sinister sent Vertigo along with the other Marauders to fight the X-Men in New York City just before the extradimensional incursion known as the "Inferno".