Xenofiction is a subgenre of science fiction encompassing stories set among species or cultures dramatically different from humanity or human society.

Examples of this kind of work include Richard Adams' Watership Down, set in the warrens of rabbits in the English countryside, and the second part of Isaac Asimov's The Gods Themselves, which describes an alien culture with three sexes, the Rational, the Emotional, and the Parental.

Another good example is The Faded Sun Trilogy: Kesrith / Shon'jir / Kutath by C. J. Cherryh. This story is about the Mri (meaning the people) -tall, secretive, bound by honor and the rigid dictates of their society. One human helps the last two survivors escape to retrace the journey of the ancestors. But he is Tsi-mri (not people), and nothing not of the people can touch that world. He must learn to become one of them -- or die at the hands of someone who has become his friend.